WIF1 anticorps

N° du produit ABIN967258

Cet anticorps Souris Monoclonal détecte spécifiquement WIF1 dans WB, IHC, ELISA et IF. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour WIF1 anticorps (ABIN967258)

Antigène: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WIF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 1G5

Détail du produit anti-WIF1 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human WIF1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-WIF1 (ABIN967258)

Veeck, Wild, Fuchs, Schüffler, Hartmann, Knüchel, Dahl: "Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer." dans: BMC cancer, Vol. 9, pp. 217, (2009) (PubMed).

Kawakami, Hirata, Yamamura, Kikuno, Saini, Majid, Tanaka, Kawamoto, Enokida, Nakagawa, Dahiya: "Functional significance of Wnt inhibitory factor-1 gene in kidney cancer." dans: Cancer research, Vol. 69, Issue 22, pp. 8603-10, (2009) (PubMed).

Détails sur WIF1

Antigène: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Autre désignation: WIF1

Sujet: The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
Synonyms: WIF-1, WIF

Poids moléculaire: 42kDa

ID gène: 11197

Pathways: Signalisation WNT, Positive Regulation of fat Cell Differentiation